ABSTRACT
Background. Acute stroke is a highly specific neurological symptom in the acute phase of COVID-19. Hemorrhagic stroke (HS) is an infrequent, but life-threatening complication of COVID-19. Objective. To analyze etiopathogenetic factors and the course of HS associated with COVID-19. Design and methods. A retrospective analysis of 27 medical histories of patients with HS associated with COVID-19 (the main group) and 14 medical histories of patients with HS not related to COVID-19 (the control group) was performed. In the main group, COVID-19 was confirmed by the positive polymerase chain reaction method. HS developed before COVID-19 symptoms in 10 (37,04 %) patients and after 4-16 days of COVID-19 symptoms onset in 17 (62,96 %) patients. Results. Our study indicates significant differences in blood pressure (BP), respiratory system parameters, laboratory data, neuroimaging data in patients of the main and control groups. Coagulopathy, thrombocytopenia, hypoxia, and the renal and hepatic failure play a significant role in the development of HS associated with COVID-19 compared to the classic HS (without COVID-19), where hypertension seems to be the important. At the same time BP is significantly lower in the main group. Conclusions. The etiopathogenetic factors and the course of HS associated with COVID-19 require pathogenetically different therapy compared to HS without COVID-19. Copyright © 2021 All-Russian Public Organization Antihypertensive League. All rights reserved.
ABSTRACT
The reaction and aggravation of the Russian economy’s problems to changes in the surrounding biological and natural processes against the background of global development trends is justified. It shows the growth of chaotic processes in the system of public relations, which inevitably leads to aggravation of relations and wars for vital space and resources, the growth of man-made and other disasters like pandemics and, in general, leads to crisis phenomena in the economy and human vulnerability in everyday life. Tasks were set and solved to find analogies for the influence of changes in the biological system, including those caused by coronavirus COVID-19 on the formation of social relations. A characteristic of the quasi-static state of the Russian economy is given, due to low growth rates, falling incomes of the population and a high proportion of the poor. The withdrawal of Russia from the quasi-static state implies the need to assess and realize the potential for growth of the Russian economy, taking into account socio-economic and natural-environmental processes. It turns out that the existing potential can provide the necessary level of development of the Russian economy and its exit from the quasi-static process, provided that sharp polarization in income is eliminated, that is, the causes of antagonization of the social sphere are eliminated. It is proved a reconfiguration of the economic mechanism of the Russian economy is required. Factors were identified and criteria were proposed that could affect Russia exit from the quasi-static state. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.